HIV infection, antiretroviral therapy initiation and longitudinal changes in biomarkers of organ function.
Identifieur interne : 002B26 ( Main/Exploration ); précédent : 002B25; suivant : 002B27HIV infection, antiretroviral therapy initiation and longitudinal changes in biomarkers of organ function.
Auteurs : Kaku A. So-Armah ; Joyce Chang ; Charles Alcorn ; Vincent Lo Re ; Jason V. Baker ; Russell Tracy ; Adeel A. Butt ; Brian K. Agan ; David Rimland ; Cynthia L. Gibert ; Matthew B. Goetz ; Krisann K. Oursler ; Maria C. Rodriguez-Barradas ; Lewis H. Kuller ; Sheldon T. Brown ; James H. Stein ; Melissa Skanderson ; Amy C. Justice ; Matthew S. Freiberg [États-Unis]Source :
- Current HIV research [ 1873-4251 ] ; 2014.
Descripteurs français
- KwdFr :
- ARN viral, Adulte, Adulte d'âge moyen, Agents antiVIH (effets indésirables), Agents antiVIH (usage thérapeutique), Anciens combattants, Diabète (sang), Femelle, Glycémie (analyse), Humains, Hypertension artérielle (physiopathologie), Hépatite C (sang), Infections à VIH (), Infections à VIH (sang), Infections à VIH (traitement médicamenteux), Inhibiteurs de l'hydroxyméthylglutaryl-CoA réductase (sang), Lipides (sang), Maladies du foie (sang), Maladies du rein (sang), Marqueurs biologiques (sang), Mâle, Numération des lymphocytes CD4, Pression sanguine, VIH-1 (Virus de l'Immunodéficience Humaine de type 1), Études longitudinales.
- MESH :
- analyse : Glycémie.
- effets indésirables : Agents antiVIH.
- physiopathologie : Hypertension artérielle.
- sang : Diabète, Hépatite C, Infections à VIH, Inhibiteurs de l'hydroxyméthylglutaryl-CoA réductase, Lipides, Maladies du foie, Maladies du rein, Marqueurs biologiques.
- traitement médicamenteux : Infections à VIH.
- usage thérapeutique : Agents antiVIH.
- ARN viral, Adulte, Adulte d'âge moyen, Anciens combattants, Femelle, Humains, Infections à VIH, Mâle, Numération des lymphocytes CD4, Pression sanguine, VIH-1 (Virus de l'Immunodéficience Humaine de type 1), Études longitudinales.
English descriptors
- KwdEn :
- Adult, Anti-HIV Agents (adverse effects), Anti-HIV Agents (therapeutic use), Biomarkers (blood), Blood Glucose (analysis), Blood Pressure, CD4 Lymphocyte Count, Diabetes Mellitus (blood), Female, HIV Infections (blood), HIV Infections (complications), HIV Infections (drug therapy), HIV-1, Hepatitis C (blood), Humans, Hydroxymethylglutaryl-CoA Reductase Inhibitors (blood), Hypertension (physiopathology), Kidney Diseases (blood), Lipids (blood), Liver Diseases (blood), Longitudinal Studies, Male, Middle Aged, RNA, Viral, Veterans.
- MESH :
- chemical , adverse effects : Anti-HIV Agents.
- chemical , analysis : Blood Glucose.
- chemical , blood : Biomarkers, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Lipids.
- chemical , therapeutic use : Anti-HIV Agents.
- blood : Diabetes Mellitus, HIV Infections, Hepatitis C, Kidney Diseases, Liver Diseases.
- complications : HIV Infections.
- drug therapy : HIV Infections.
- physiopathology : Hypertension.
- Adult, Blood Pressure, CD4 Lymphocyte Count, Female, HIV-1, Humans, Longitudinal Studies, Male, Middle Aged, RNA, Viral, Veterans.
Abstract
HIV is associated with end-organ diseases of aging via unclear mechanisms. Longitudinally assessing how HIV infection and ART initiation affect biomarkers of end organ function/disease could clarify these mechanisms. We investigated longitudinal changes in clinical biomarkers following 1) HIV infection and 2) ART initiation with evidence of viral suppression.
PubMed: 25034208
Affiliations:
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Le document en format XML
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So-Armah</name></author><author><name sortKey="Chang, Joyce" sort="Chang, Joyce" uniqKey="Chang J" first="Joyce" last="Chang">Joyce Chang</name></author><author><name sortKey="Alcorn, Charles" sort="Alcorn, Charles" uniqKey="Alcorn C" first="Charles" last="Alcorn">Charles Alcorn</name></author><author><name sortKey="Lo Re, Vincent" sort="Lo Re, Vincent" uniqKey="Lo Re V" first="Vincent" last="Lo Re">Vincent Lo Re</name></author><author><name sortKey="Baker, Jason V" sort="Baker, Jason V" uniqKey="Baker J" first="Jason V" last="Baker">Jason V. Baker</name></author><author><name sortKey="Tracy, Russell" sort="Tracy, Russell" uniqKey="Tracy R" first="Russell" last="Tracy">Russell Tracy</name></author><author><name sortKey="Butt, Adeel A" sort="Butt, Adeel A" uniqKey="Butt A" first="Adeel A" last="Butt">Adeel A. Butt</name></author><author><name sortKey="Agan, Brian K" sort="Agan, Brian K" uniqKey="Agan B" first="Brian K" last="Agan">Brian K. 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Kuller</name></author><author><name sortKey="Brown, Sheldon T" sort="Brown, Sheldon T" uniqKey="Brown S" first="Sheldon T" last="Brown">Sheldon T. Brown</name></author><author><name sortKey="Stein, James H" sort="Stein, James H" uniqKey="Stein J" first="James H" last="Stein">James H. Stein</name></author><author><name sortKey="Skanderson, Melissa" sort="Skanderson, Melissa" uniqKey="Skanderson M" first="Melissa" last="Skanderson">Melissa Skanderson</name></author><author><name sortKey="Justice, Amy C" sort="Justice, Amy C" uniqKey="Justice A" first="Amy C" last="Justice">Amy C. Justice</name></author><author><name sortKey="Freiberg, Matthew S" sort="Freiberg, Matthew S" uniqKey="Freiberg M" first="Matthew S" last="Freiberg">Matthew S. Freiberg</name><affiliation wicri:level="2"><nlm:affiliation>230 McKee Place, Pittsburgh, PA 15213, USA. freibergms@upmc.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>230 McKee Place, Pittsburgh, PA 15213</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author></analytic><series><title level="j">Current HIV research</title><idno type="eISSN">1873-4251</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Anti-HIV Agents (adverse effects)</term><term>Anti-HIV Agents (therapeutic use)</term><term>Biomarkers (blood)</term><term>Blood Glucose (analysis)</term><term>Blood Pressure</term><term>CD4 Lymphocyte Count</term><term>Diabetes Mellitus (blood)</term><term>Female</term><term>HIV Infections (blood)</term><term>HIV Infections 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médicamenteux)</term><term>Inhibiteurs de l'hydroxyméthylglutaryl-CoA réductase (sang)</term><term>Lipides (sang)</term><term>Maladies du foie (sang)</term><term>Maladies du rein (sang)</term><term>Marqueurs biologiques (sang)</term><term>Mâle</term><term>Numération des lymphocytes CD4</term><term>Pression sanguine</term><term>VIH-1 (Virus de l'Immunodéficience Humaine de type 1)</term><term>Études longitudinales</term></keywords><keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Anti-HIV Agents</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>Blood Glucose</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Biomarkers</term><term>Hydroxymethylglutaryl-CoA Reductase Inhibitors</term><term>Lipids</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Anti-HIV Agents</term></keywords><keywords scheme="MESH" qualifier="analyse" xml:lang="fr"><term>Glycémie</term></keywords><keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>Diabetes Mellitus</term><term>HIV Infections</term><term>Hepatitis C</term><term>Kidney Diseases</term><term>Liver Diseases</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>HIV Infections</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>HIV Infections</term></keywords><keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Agents antiVIH</term></keywords><keywords scheme="MESH" qualifier="physiopathologie" xml:lang="fr"><term>Hypertension artérielle</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Hypertension</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Diabète</term><term>Hépatite C</term><term>Infections à VIH</term><term>Inhibiteurs de l'hydroxyméthylglutaryl-CoA réductase</term><term>Lipides</term><term>Maladies du foie</term><term>Maladies du rein</term><term>Marqueurs biologiques</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Infections à VIH</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Agents antiVIH</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Blood Pressure</term><term>CD4 Lymphocyte Count</term><term>Female</term><term>HIV-1</term><term>Humans</term><term>Longitudinal Studies</term><term>Male</term><term>Middle Aged</term><term>RNA, Viral</term><term>Veterans</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>ARN viral</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Anciens combattants</term><term>Femelle</term><term>Humains</term><term>Infections à VIH</term><term>Mâle</term><term>Numération des lymphocytes CD4</term><term>Pression sanguine</term><term>VIH-1 (Virus de l'Immunodéficience Humaine de type 1)</term><term>Études longitudinales</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">HIV is associated with end-organ diseases of aging via unclear mechanisms. Longitudinally assessing how HIV infection and ART initiation affect biomarkers of end organ function/disease could clarify these mechanisms. We investigated longitudinal changes in clinical biomarkers following 1) HIV infection and 2) ART initiation with evidence of viral suppression.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Pennsylvanie</li></region></list><tree><noCountry><name sortKey="Agan, Brian K" sort="Agan, Brian K" uniqKey="Agan B" first="Brian K" last="Agan">Brian K. Agan</name><name sortKey="Alcorn, Charles" sort="Alcorn, Charles" uniqKey="Alcorn C" first="Charles" last="Alcorn">Charles Alcorn</name><name sortKey="Baker, Jason V" sort="Baker, Jason V" uniqKey="Baker J" first="Jason V" last="Baker">Jason V. Baker</name><name sortKey="Brown, Sheldon T" sort="Brown, Sheldon T" uniqKey="Brown S" first="Sheldon T" last="Brown">Sheldon T. Brown</name><name sortKey="Butt, Adeel A" sort="Butt, Adeel A" uniqKey="Butt A" first="Adeel A" last="Butt">Adeel A. Butt</name><name sortKey="Chang, Joyce" sort="Chang, Joyce" uniqKey="Chang J" first="Joyce" last="Chang">Joyce Chang</name><name sortKey="Gibert, Cynthia L" sort="Gibert, Cynthia L" uniqKey="Gibert C" first="Cynthia L" last="Gibert">Cynthia L. Gibert</name><name sortKey="Goetz, Matthew B" sort="Goetz, Matthew B" uniqKey="Goetz M" first="Matthew B" last="Goetz">Matthew B. Goetz</name><name sortKey="Justice, Amy C" sort="Justice, Amy C" uniqKey="Justice A" first="Amy C" last="Justice">Amy C. Justice</name><name sortKey="Kuller, Lewis H" sort="Kuller, Lewis H" uniqKey="Kuller L" first="Lewis H" last="Kuller">Lewis H. Kuller</name><name sortKey="Lo Re, Vincent" sort="Lo Re, Vincent" uniqKey="Lo Re V" first="Vincent" last="Lo Re">Vincent Lo Re</name><name sortKey="Oursler, Krisann K" sort="Oursler, Krisann K" uniqKey="Oursler K" first="Krisann K" last="Oursler">Krisann K. Oursler</name><name sortKey="Rimland, David" sort="Rimland, David" uniqKey="Rimland D" first="David" last="Rimland">David Rimland</name><name sortKey="Rodriguez Barradas, Maria C" sort="Rodriguez Barradas, Maria C" uniqKey="Rodriguez Barradas M" first="Maria C" last="Rodriguez-Barradas">Maria C. Rodriguez-Barradas</name><name sortKey="Skanderson, Melissa" sort="Skanderson, Melissa" uniqKey="Skanderson M" first="Melissa" last="Skanderson">Melissa Skanderson</name><name sortKey="So Armah, Kaku A" sort="So Armah, Kaku A" uniqKey="So Armah K" first="Kaku A" last="So-Armah">Kaku A. So-Armah</name><name sortKey="Stein, James H" sort="Stein, James H" uniqKey="Stein J" first="James H" last="Stein">James H. Stein</name><name sortKey="Tracy, Russell" sort="Tracy, Russell" uniqKey="Tracy R" first="Russell" last="Tracy">Russell Tracy</name></noCountry><country name="États-Unis"><region name="Pennsylvanie"><name sortKey="Freiberg, Matthew S" sort="Freiberg, Matthew S" uniqKey="Freiberg M" first="Matthew S" last="Freiberg">Matthew S. Freiberg</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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